The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external pH.

ABSTRACT: Streptococcus mutans F-ATPase, the major component of the acid-adaptive response of the organism, is transcriptionally upregulated at low pH. Fusions of the F-ATPase promoter to chloramphenicol acetyltransferase indicated that pH-dependent expression is still observed with a short promoter that contains a domain conserved between streptococcal ATPase operons.

SUBMITTER: Kuhnert WL 

PROVIDER: S-EPMC532412 | biostudies-literature | 2004 Dec

REPOSITORIES: biostudies-literature