MinorityReport, software for generalized analysis of causal genetic variants.

ABSTRACT:

Background

The widespread availability of next generation genome sequencing technologies has enabled a wide range of variant detection applications, especially in cancer and inborn genetic disorders. For model systems and microorganisms, the same technology may be used to discover the causative mutations for any phenotype, including those generated in response to chemical perturbation. In the case of pathogenic organisms, these approaches have allowed the determination of drug targets by means of resistance selection followed by genome sequencing.

Results

MinorityReport is open source software written in python that facilitates the comparison of any two sets of genome alignments for the purpose of rapidly identifying the spectrum of nonsynonymous changes, insertions or delet

SUBMITTER: Horst JA 

PROVIDER: S-EPMC5324306 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature