Fully Implanted Brain-Computer Interface in a Locked-In Patient with ALS.

ABSTRACT: Options for people with severe paralysis who have lost the ability to communicate orally are limited. We describe a method for communication in a patient with late-stage amyotrophic lateral sclerosis (ALS), involving a fully implanted brain-computer interface that consists of subdural electrodes placed over the motor cortex and a transmitter placed subcutaneously in the left side of the thorax. By attempting to move the hand on the side opposite the implanted electrodes, the patient accurately and independently controlled a computer typing program 28 weeks after electrode placement, at the equivalent of two letters per minute. The brain-computer interface offered autonomous communication that supplemented and at times supplanted the patient's eye-tracking device. (Funded by the Government

SUBMITTER: Vansteensel MJ 

PROVIDER: S-EPMC5326682 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature