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Facile silicification of plastic surface for bioassays.


ABSTRACT: We herein report a biomimetic technique to modify plastic substrates for bioassays. The method first places a polydopamine adhesion layer to plastic surface, and then grows conformal silica coating. As proof of principle, we coated plastic microbeads to construct a disposable filter for point-of-care nucleic acid extraction.

SUBMITTER: Hong S 

PROVIDER: S-EPMC5327824 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Facile silicification of plastic surface for bioassays.

Hong Seonki S   Park Ki Soo KS   Weissleder Ralph R   Castro Cesar M CM   Lee Hakho H  

Chemical communications (Cambridge, England) 20170201 13


We herein report a biomimetic technique to modify plastic substrates for bioassays. The method first places a polydopamine adhesion layer to plastic surface, and then grows conformal silica coating. As proof of principle, we coated plastic microbeads to construct a disposable filter for point-of-care nucleic acid extraction. ...[more]

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