Percutaneous Coronary Intervention Versus Optimal Medical Therapy for Stable Angina in Advanced CKD: A Decision Analysis.

ABSTRACT:

Background

Percutaneous coronary intervention (PCI) use is low in the setting of stable symptomatic angina in individuals with advanced chronic kidney disease (CKD) despite high cardiovascular risk in this population, and PCI is frequently deferred out of concern for precipitating dialysis therapy. Whether this is appropriate is uncertain, and patient-centered data comparing the relative risks and benefits of continued medical therapy versus PCI in patients with advanced CKD and stable angina are scarce.

Study design

Decision analysis.

Setting & population

Hypothetical cohort of individuals with advanced CKD (stages 4-5 with estimated glomerular filtration rates ≤ 20mL/min/1.73m²) and stable angina.

Model, perspective, & timeline

A Markov model with

SUBMITTER: Khattak A 

PROVIDER: S-EPMC5329119 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature