Non-traumatic keratitis due to Colletotrichum truncatum.

ABSTRACT:

Introduction

The fungal genus Colletotrichum is an uncommon cause of human infections. It has been implicated in cutaneous phaeohyphomycosis, artritis and keratitis secondary to traumatic implantation.

Case presentation

We report two cases of keratitis due Colletotrichum truncatum in middle-aged, immunocompetent persons without history of trauma. The aetiological agents were identified based on DNA sequencing. Azoles and echinocandins showed high minimal inhibitory concentrations while amphotericin B was ≤ 0.25  mg l^-1. Both patients failed topical antifungal treatment and needed penetrating keratoplasty with a favourable outcome.

Conclusion

C. truncatum caused keratomycosis which did not respond to topical antifungal agents. To the bes

SUBMITTER: Llamos R 

PROVIDER: S-EPMC5330238 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature