Correlation analysis between ultrasound findings and abnormal karyotypes in the embryos from early pregnancy loss after in vitro fertilization-embryo transfer.

ABSTRACT:

Purpose

The purpose of the study is to evaluate the correlation between ultrasound findings and abnormal karyotypes in early pregnancy losses (EPLs) after in vitro fertilization-embryo transfer (IVF-ET).

Methods

This retrospective analysis assessed 2172 cases of EPL after IVF-ET occurring between January 2008 and December 2013. The cases were examined via transvaginal ultrasonography (TVS). Embryonic tissue karyotyping following miscarriage was performed using a comparative genomic hybridization (CGH) analysis with fluorescence in situ hybridization (FISH). The correlations between the ultrasound findings and the karyotypes were evaluated.

Results

Six categories of ultrasound findings were observed: normal ultrasound, empty sac, yolk sac only, small gestational sac, s

SUBMITTER: Li X 

PROVIDER: S-EPMC5330976 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature