Intact Imaging of Human Heart Structure Using X-ray Phase-Contrast Tomography.

ABSTRACT: Structural examination of human heart specimens at the microscopic level is a prerequisite for understanding congenital heart diseases. It is desirable not to destroy or alter the properties of such specimens because of their scarcity. However, many of the currently available imaging techniques either destroy the specimen through sectioning or alter the chemical and mechanical properties of the specimen through staining and contrast agent injection. As a result, subsequent studies may not be possible. X-ray phase-contrast tomography is an imaging modality for biological soft tissues that does not destroy or alter the properties of the specimen. The feasibility of X-ray phase-contrast tomography for the structural examination of heart specimens was tested using infantile and fetal heart spe

SUBMITTER: Kaneko Y 

PROVIDER: S-EPMC5331087 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature