Asymptomatic hyperuricemia is a strong risk factor for resistant hypertension in elderly subjects from general population.

ABSTRACT:

Objective

In clinical practice, patient characteristics predicting resistant hypertension (RH) include higher blood pressure levels, left ventricular hypertrophy, older age, obesity, chronic kidney disease and diabetes. On the contrary little is known about the role of serum uric acid (SUA) as a risk factor for RH in subjects from general population.

Material and methods

580 elderly subjects aged ≥65 years were enrolled in the Risk Of Vascular complications Impact of Genetics in Old people (ROVIGO) study. RH was defined as the failure to maintain blood pressure values below 140mmHg (systolic) and 90mmHg (diastolic) despite therapeutic interventions that include appropriate lifestyle measures plus adherence to treatment with full doses of at least three antihypertensive drugs

SUBMITTER: Mazza A 

PROVIDER: S-EPMC5331939 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature