Temporal stability of multiple response systems to 7.5% carbon dioxide challenge.

ABSTRACT: Self-reported anxiety, and potentially physiological response, to maintained inhalation of carbon dioxide (CO₂) enriched air shows promise as a putative marker of panic reactivity and vulnerability. Temporal stability of response systems during low-dose, steady-state CO₂ breathing challenge is lacking. Outcomes on multiple levels were measured two times, one week apart, in 93 individuals. Stability was highest during the CO₂ breathing phase compared to pre-CO₂ and recovery phases, with anxiety ratings, respiratory rate, skin conductance level, and heart rate demonstrating good to excellent temporal stability (ICCs≥0.71). Cognitive symptoms tied to panic were somewhat less stable (ICC=0.58) than physical symptoms (ICC=0.74) during CO₂ b

SUBMITTER: Roberson-Nay R 

PROVIDER: S-EPMC5331940 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature