Effects of different phosphate lowering strategies in patients with CKD on laboratory outcomes: A systematic review and NMA.

ABSTRACT:

Background

Chronic kidney disease-mineral and bone disorder (CKD-MBD), a complication of chronic kidney disease, has been linked to reduced quality and length of life. High serum phosphate levels that result from CKD-MBD require phosphate-lowering agents, also known as phosphate binders. The objective of this systematic review is to compare the effects of available phosphate binders on laboratory outcomes in patients with CKD-MBD.

Methods

Data sources included MEDLINE and EMBASE from January 1996 to April 2016, and the Cochrane Register of Controlled Trials up to April 2016. Teams of two reviewers, independently and in duplicate, screened titles and abstracts and potentially eligible full text reports to determine eligibility, and subsequently abstracted data and assessed ri

SUBMITTER: Sekercioglu N 

PROVIDER: S-EPMC5331957 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature