Characterization of dependencies between growth and division in budding yeast.

ABSTRACT: Cell growth and division are processes vital to the proliferation and development of life. Coordination between these two processes has been recognized for decades in a variety of organisms. In the budding yeast Saccharomyces cerevisiae, this coordination or 'size control' appears as an inverse correlation between cell size and the rate of cell-cycle progression, routinely observed in G₁ prior to cell division commitment. Beyond this point, cells are presumed to complete S/G₂/M at similar rates and in a size-independent manner. As such, studies of dependence between growth and division have focused on G₁ Moreover, in unicellular organisms, coordination between growth and division has commonly been analysed within the cycle of a single cell wit

SUBMITTER: Mayhew MB 

PROVIDER: S-EPMC5332586 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature