Regulation of infection efficiency in a globally abundant marine Bacteriodetes virus.

ABSTRACT: Bacteria impact humans, industry and nature, but do so under viral constraints. Problematically, knowledge of viral infection efficiencies and outcomes derives from few model systems that over-represent efficient lytic infections and under-represent virus-host natural diversity. Here we sought to understand infection efficiency regulation in an emerging environmental Bacteroidetes-virus model system with markedly different outcomes on two genetically and physiologically nearly identical host strains. For this, we quantified bacterial virus (phage) and host DNA, transcripts and phage particles throughout both infections. While phage transcriptomes were similar, transcriptional differences between hosts suggested host-derived regulation of infection efficiency. Specifically, the alternative

SUBMITTER: Howard-Varona C 

PROVIDER: S-EPMC5335546 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature