Estimating Optical Coherence Tomography Structural Measurement Floors to Improve Detection of Progression in Advanced Glaucoma.

ABSTRACT:

Purpose

"Floor effects" in retinal imaging are defined as the points at which no further structural loss can be detected. We estimated the measurement floors for spectral-domain optical coherence tomography (SDOCT) measurements and compared global change over time in advanced glaucoma eyes.

Design

Validity study to investigate measurement floors.

Methods

A longitudinal "Variability group" of 41 eyes with moderate to advanced glaucoma (standard automated perimetry mean deviation ≤-8 dB) was used to estimate measurement floors. Minimum rim width (MRW), ganglion cell-inner plexiform layer thickness (GC-IPLT), and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) were determined. Floors were defined as the average image area with a loss less than first-percent

SUBMITTER: Bowd C 

PROVIDER: S-EPMC5337134 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature