Network theory may explain the vulnerability of medieval human settlements to the Black Death pandemic.

ABSTRACT: Epidemics can spread across large regions becoming pandemics by flowing along transportation and social networks. Two network attributes, transitivity (when a node is connected to two other nodes that are also directly connected between them) and centrality (the number and intensity of connections with the other nodes in the network), are widely associated with the dynamics of transmission of pathogens. Here we investigate how network centrality and transitivity influence vulnerability to diseases of human populations by examining one of the most devastating pandemic in human history, the fourteenth century plague pandemic called Black Death. We found that, after controlling for the city spatial location and the disease arrival time, cities with higher values of both centrality and transit

SUBMITTER: Gomez JM 

PROVIDER: S-EPMC5338018 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature