HY5, a positive regulator of light signaling, negatively controls the unfolded protein response in Arabidopsis.

ABSTRACT: Light influences essentially all aspects of plant growth and development. Integration of light signaling with different stress response results in improvement of plant survival rates in ever changing environmental conditions. Diverse environmental stresses affect the protein-folding capacity of the endoplasmic reticulum (ER), thus evoking ER stress in plants. Consequently, the unfolded protein response (UPR), in which a set of molecular chaperones is expressed, is initiated in the ER to alleviate this stress. Although its underlying molecular mechanism remains unknown, light is believed to be required for the ER stress response. In this study, we demonstrate that increasing light intensity elevates the ER stress sensitivity of plants. Moreover, mutation of the ELONGATED HYPOCOTYL 5 (HY5),

SUBMITTER: Nawkar GM 

PROVIDER: S-EPMC5338426 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature