Measurement of perihematomal edema in intracerebral hemorrhage.

ABSTRACT:

Background and purpose

Perihematomal edema (PHE) is a marker of secondary injury in intracerebral hemorrhage (ICH). PHE measurement on computed tomography (CT) is challenging, and the principles used to detect PHE have not been described fully. We developed a systematic approach for CT-based measurement of PHE.

Methods

Two independent raters measured PHE volumes on baseline and 24-hour post-ICH CT scans of 20 primary supratentorial ICH subjects. Boundaries were outlined with an edge-detection tool and adjusted after inspection of the 3 orthogonal planes. PHE was delineated with the additional principle that it should be (a) more hypodense than the corresponding area in the contralateral hemisphere and (b) most hypodense immediately surrounding the hemorrhage. We examined int

SUBMITTER: Urday S 

PROVIDER: S-EPMC5340416 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature