Effects of early parenteral iron combined erythropoietin in preterm infants: A randomized controlled trial.

ABSTRACT:

Backgroud

The aim of the study was to evaluate the effect of early parenteral iron supplementation combined erythropoietin for prevention of anemia in preterm infants.

Methods

In total, 96 preterm infants were randomly assigned to 3 groups: a control group receiving standard parenteral nutrition (group 1: n = 31), an iron-supplemented group (group 2: IS, n = 33), and an iron-supplemented combined erythropoietin group (group 3: IS+EPO, n = 32). The primary objective was to assess hemoglobin (Hb) levels. The secondary objectives included assessment of red blood cell counts (RBC), mean cell volume (MCV), serum iron, ferritin, percentages of reticulocyte (RET), total iron binding capacity (TIBC) and oxidative stress, which was assessed by measuring plasma levels of malondialdehy

SUBMITTER: Qiao L 

PROVIDER: S-EPMC5340423 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature