Calculating Power by Bootstrap, with an Application to Cluster-Randomized Trials.

ABSTRACT:

Background

A key requirement for a useful power calculation is that the calculation mimic the data analysis that will be performed on the actual data, once that data is observed. Close approximations may be difficult to achieve using analytic solutions, however, and thus Monte Carlo approaches, including both simulation and bootstrap resampling, are often attractive. One setting in which this is particularly true is cluster-randomized trial designs. However, Monte Carlo approaches are useful in many additional settings as well. Calculating power for cluster-randomized trials using analytic or simulation-based methods is frequently unsatisfactory due to the complexity of the data analysis methods to be employed and to the sparseness of data to inform the choice of important paramete

SUBMITTER: Kleinman K 

PROVIDER: S-EPMC5340517 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature