Social and economic consequences of alcohol use disorder: a longitudinal cohort and co-relative analysis.

ABSTRACT:

Background

Although alcohol use disorder (AUD) is associated with future risk for psychosocial dysfunction, the degree to which this arises from a direct causal effect of AUD on functioning v. from correlated risk factors (also known as confounders) is less clearly established.

Method

AUD was assessed from Swedish medical, criminal and pharmacy registries. In a large general population cohort, using Cox proportional hazard and regression models, we predicted from the onset of AUD four outcomes: early retirement, unemployment, social assistance, and individual income. We then examined the degree to which these associations were attenuated by relevant confounders as well as by the use of discordant cousin, half-sibling, full-sibling, and monozygotic twin pairs.

Results

SUBMITTER: Kendler KS 

PROVIDER: S-EPMC5340576 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature