Auditory evoked arousal responses of 3-month-old infants exposed to methamphetamine in utero: a nap study.

ABSTRACT:

Aim

To investigate whether or not infants exposed to methamphetamine prenatally have impaired arousal responses from sleep.

Methods

The polygraphic nap studies involved 42 infants aged 3 months exposed to methamphetamine in utero and a comparison group of 57 infants. A proportion of mothers in both groups smoked cigarettes and/or marijuana and drank alcohol during pregnancy. White noise from 50 to 100 decibels (dB) was administered at 10 dB intervals twice within non-rapid eye movement (NREM) and rapid eye movement (REM) sleep states and arousal thresholds measured.

Results

Combining groups, 306 tests were completed (128 and 178 within REM and NREM sleep, respectively) and infants were more likely to wake at lower thresholds in REM than NREM sleep (hazard ratio 5.58;

SUBMITTER: Galland BC 

PROVIDER: S-EPMC5341078 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature