Genetic affinities among the historical provinces of Romania and Central Europe as revealed by an mtDNA analysis.

ABSTRACT:

Background

As a major crossroads between Asia and Europe, Romania has experienced continuous migration and invasion episodes. The precise routes may have been shaped by the topology of the territory and had diverse impacts on the genetic structure of mitochondrial DNA (mtDNA) in historical Romanian provinces. We studied 714 Romanians from all historical provinces, Wallachia, Dobrudja, Moldavia, and Transylvania, by analyzing the mtDNA control region and coding markers to encompass the complete landscape of mtDNA haplogroups.

Results

We observed a homogenous distribution of the majority of haplogroups among the Romanian provinces and a clear association with the European populations. A principal component analysis and multidimensional scaling analysis supported the genetic si

SUBMITTER: Cocos R 

PROVIDER: S-EPMC5341396 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature