Demographics, epidemiology and the impact of vaccination campaigns in a measles-free world - Can elimination be maintained?

ABSTRACT:

Introduction

All six WHO regions currently have goals for measles elimination by 2020. Measles vaccination is delivered via routine immunization programmes, which in most sub-Saharan African countries reach children around 9months of age, and supplementary immunization activities (SIAs), which target a wider age range at multi-annual intervals. In the absence of endemic measles circulation, the proportion of individuals susceptible to measles will gradually increase through accumulation of new unvaccinated individuals in each birth cohort, increasing the risk of an epidemic. The impact of SIAs and the financial investment they require, depend on coverage and target age range.

Materials and methods

We evaluated the impact of target population age range for periodic SIAs, eval

SUBMITTER: Prada JM 

PROVIDER: S-EPMC5341736 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature