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Hormone receptor status may impact the survival benefit of surgery in stage iv breast cancer: a population-based study.


ABSTRACT:

Introduction

The role of surgery in stage IV breast cancer is controversial. We used the Surveillance, Epidemiology, and End Results database to explore the impact of surgery on the survival of patients with stage IV breast cancer.

Methods

In total, 10,441 eligible stage IV breast cancer patients from 2004 to 2008 were included. They were divided into four groups as follows: R0 group (patients who underwent primary site and distant metastatic site resection), primary site resection group, metastases resection group, and no resection group.

Results

The four groups achieved a median survival time (MST) of 51, 43, 31 and 21 months, respectively, P < 0.001. The Cox proportional hazards model showed that the R0 group, primary resection group and metastases resection group

SUBMITTER: Tan Y 

PROVIDER: S-EPMC5342604 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature