Parietal operculum and motor cortex activities predict motor recovery in moderate to severe stroke.

ABSTRACT: While motor recovery following mild stroke has been extensively studied with neuroimaging, mechanisms of recovery after moderate to severe strokes of the types that are often the focus for novel restorative therapies remain obscure. We used fMRI to: 1) characterize reorganization occurring after moderate to severe subacute stroke, 2) identify brain regions associated with motor recovery and 3) to test whether brain activity associated with passive movement measured in the subacute period could predict motor outcome six months later. Because many patients with large strokes involving sensorimotor regions cannot engage in voluntary movement, we used passive flexion-extension of the paretic wrist to compare 21 patients with subacute ischemic stroke to 24 healthy controls one month after strok

SUBMITTER: Hannanu FF 

PROVIDER: S-EPMC5342999 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature