Redefining radiotherapy for early-stage breast cancer with single dose ablative treatment: a study protocol.

ABSTRACT:

Background

A shift towards less burdening and more patient friendly treatments for breast cancer is currently ongoing. In low-risk patients with early-stage disease, accelerated partial breast irradiation (APBI) is an alternative for whole breast irradiation following breast-conserving surgery. MRI-guided single dose ablative APBI has the potential to offer a minimally burdening, non-invasive treatment that could replace current breast-conserving therapy.

Methods

The ABLATIVE study is a prospective, single arm, multicenter study evaluating preoperative, single dose, ablative radiation treatment in patients with early-stage breast cancer. Patients with core biopsy proven non-lobular invasive breast cancer, (estrogen receptor positive, Her2 negative, maximum tumor size 3.0 cm

SUBMITTER: Charaghvandi RK 

PROVIDER: S-EPMC5343419 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature