Ischemic lesions, blood pressure dysregulation, and poor outcomes in intracerebral hemorrhage.

ABSTRACT:

Objective

To evaluate the associations among diffusion-weighted imaging (DWI) lesions, blood pressure (BP) dysregulation, MRI markers of small vessel disease, and poor outcome in a large, prospective study of primary intracerebral hemorrhage (ICH).

Methods

The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a multicenter, observational study of ICH among white, black, and Hispanic patients.

Results

Of 600 patients, mean (±SD) age was 60.8 ± 13.6 years, median (interquartile range) ICH volume was 9.1 mL (3.5-20.8), and 79.6% had hypertension. Overall, 26.5% of cases had DWI lesions, and this frequency differed by race/ethnicity (black 33.8%, Hispanic 24.9%, white 20.2%, overall p = 0.006). A logistic regression model of variables associated

SUBMITTER: Kidwell CS 

PROVIDER: S-EPMC5344081 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature