Equine Dental Pulp Connective Tissue Particles Reduced Lameness in Horses in a Controlled Clinical Trial.

ABSTRACT:

Objective

To assess if injection of allogeneic dental pulp tissue particles would improve lameness in horses with naturally occurring osteoarthritis (OA) or soft tissue (ST) injury.

Design

Prospective, randomized, blinded, and controlled clinical trial and client survey assessment.

Animals

Forty lame client-owned horses.

Procedures

Sterile dental pulp, recovered from otherwise healthy foals that perish during dystocia, was processed under good manufacturing processing to produce mechanically manipulated, unexpanded pulp tissue particles containing viable cells surrounded in extracellular matrix. Forty lame client-owned horses with confirmed OA (n = 20), or ST injury (desmitis or tendonitis) received a 2 mL intra-articular (n = 20 OA) or intra-lesi

SUBMITTER: Bertone AL 

PROVIDER: S-EPMC5344919 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature