Effect of excess iodine intake on thyroid diseases in different populations: A systematic review and meta-analyses including observational studies.

ABSTRACT:

Background

Although several reports concerning the association of iodine excess and thyroid disease have appeared, no systematic review of the association between iodine excess intake and thyroid diseases, especially hyperthyroidism and hypothyroidism, has yet been reported.

Method

We conducted a systematic search of Ovid MEDLINE, PubMed, Cochrane Central Register of Controlled Trials databases, Ichushi-Web and CiNii database for intervention trials and observational studies. Search terms were constructed from related words for excess AND iodine intake or excretion AND thyroid hormones or diseases AND study designs. After considering the qualitative heterogeneity among studies, a meta-analysis was conducted and odds ratios and 95% confidence intervals (CI) were estimated in

SUBMITTER: Katagiri R 

PROVIDER: S-EPMC5345857 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature