Incidence of Hepatocellular Carcinoma in All 50 United States, From 2000 Through 2012.

ABSTRACT:

Background & aims

The incidence and mortality of hepatocellular carcinoma (HCC) have been reported to be plateauing in the United States. The United States has large racial, ethnic, and regional variation; we collected data from all 50 states to better analyze changes in HCC incidence in the entire United States.

Methods

We collected data from the US Cancer Statistics registry, which covers 97% of the population, and calculated adjusted incidence rates. We assessed annual trends among sociodemographic and geographic subgroups using joinpoint analysis.

Results

HCC incidence increased from 4.4/100,000 in 2000 to 6.7/100,000 in 2012, increasing by 4.5% (95% confidence interval [CI], 4.3%-4.7%) annually between 2000 and 2009, but only by 0.7% annually (95% CI, -0.2% to 1.

SUBMITTER: White DL 

PROVIDER: S-EPMC5346030 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature