Rapid development of entity-based data models for bioinformatics with persistence object-oriented design and structured interfaces.

ABSTRACT: Databases are imperative for research in bioinformatics and computational biology. Current challenges in database design include data heterogeneity and context-dependent interconnections between data entities. These challenges drove the development of unified data interfaces and specialized databases. The curation of specialized databases is an ever-growing challenge due to the introduction of new data sources and the emergence of new relational connections between established datasets. Here, an open-source framework for the curation of specialized databases is proposed. The framework supports user-designed models of data encapsulation, objects persistency and structured interfaces to local and external data sources such as MalaCards, Biomodels and the National Centre for Biotechnology Inf

SUBMITTER: Ezra Tsur E 

PROVIDER: S-EPMC5346198 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature