The role of genes, intelligence, personality, and social engagement in cognitive performance in Klinefelter syndrome.

ABSTRACT:

Introduction

The determinants of cognitive deficits among individuals with Klinefelter syndrome (KS) are not well understood. This study was conducted to assess the impact of general intelligence, personality, and social engagement on cognitive performance among patients with KS and a group of controls matched for age and years of education.

Methods

Sixty-nine patients with KS and 69 controls were assessed in terms of IQ, NEO personality inventory, the Autism Spectrum Quotient (AQ) scale, and measures of cognitive performance reflecting working memory and executive function.

Results

Patients with KS performed more poorly on memory and executive-function tasks. Patients with KS also exhibited greater neuroticism and less extraversion, openness, and conscientiousness th

SUBMITTER: Skakkebæk A 

PROVIDER: S-EPMC5346527 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature