Canine leishmaniosis caused by Leishmania major and Leishmania tropica: comparative findings and serology.

ABSTRACT:

Background

Infection and clinical disease associated with Leishmania major and Leishmania tropica, two common agents of human cutaneous leishmaniosis, have rarely been reported in dogs. This study describes dogs infected with these Leishmania spp. prevalent in the Middle East and North Africa, and compares the serological response of dogs infected with Leishmania infantum, L. major or L. tropica to whole promastigote antigen enzyme-linked immunosorbent assay (ELISA) of each species and to rK39 dipstick.

Results

Leishmania major infection in a 5-month-old male dog was associated with alopecic and ulcerative periocular and limb skin lesions which responded to allopurinol treatment. Infection was detected by skin and blood polymerase chain reaction (PCR) and confirmed by DNA se

SUBMITTER: Baneth G 

PROVIDER: S-EPMC5346844 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature