Ontology highlight
ABSTRACT:
SUBMITTER: Tsuyama T
PROVIDER: S-EPMC5346966 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Tsuyama Taiichi T Tsubouchi Asako A Usui Tadao T Imamura Hiromi H Uemura Tadashi T
The Journal of cell biology 20170216 3
Mitochondria are key contributors to the etiology of diseases associated with neuromuscular defects or neurodegeneration. How changes in cellular metabolism specifically impact neuronal intracellular processes and cause neuropathological events is still unclear. We here dissect the molecular mechanism by which mitochondrial dysfunction induced by Prel aberrant function mediates selective dendritic loss in <i>Drosophila melanogaster</i> class IV dendritic arborization neurons. Using in vivo ATP i ...[more]