The Impact of Smoking Very Low Nicotine Content Cigarettes on Alcohol Use.

ABSTRACT:

Background

Reducing the nicotine content in cigarettes could improve public health by reducing smoking and toxicant exposure, but may also have unintended consequences on alcohol use. The primary objective of this study was to examine the effect of reducing the nicotine content in cigarettes on alcohol outcomes. The secondary aim was to examine whether the effects of these cigarettes on alcohol outcomes were mediated by changes in nicotine exposure, smoking behavior, or withdrawal.

Methods

Between June 2013 and July 2014, we conducted a 7-arm, double-blind, randomized clinical trial at 10 U.S.-based sites. Daily smokers not currently interested in quitting (n = 839) were assigned to equally sized groups to smoke for 6 weeks cigarettes containing either normal nicotine conten

SUBMITTER: Dermody SS 

PROVIDER: S-EPMC5347256 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature