Clustered brachiopod Hox genes are not expressed collinearly and are associated with lophotrochozoan novelties.

ABSTRACT: Temporal collinearity is often considered the main force preserving Hox gene clusters in animal genomes. Studies that combine genomic and gene expression data are scarce, however, particularly in invertebrates like the Lophotrochozoa. As a result, the temporal collinearity hypothesis is currently built on poorly supported foundations. Here we characterize the complement, cluster, and expression of Hox genes in two brachiopod species, Terebratalia transversa and Novocrania anomalaT. transversa has a split cluster with 10 genes (lab, pb, Hox3, Dfd, Scr, Lox5, Antp, Lox4, Post2, and Post1), whereas N. anomala has 9 genes (apparently missing Post1). Our in situ hybridization, real-time quan

SUBMITTER: Schiemann SM 

PROVIDER: S-EPMC5347542 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature