Biosynthetic pathway of aliphatic formates via a Baeyer-Villiger oxidation in mechanism present in astigmatid mites.

ABSTRACT: Astigmatid mites depend on bioactive glandular secretions, pheromones, and defensive agents to mediate intra- and interspecies interactions. Aliphatic formates, such as (Z,Z)-8,11-heptadecadienyl formate (8,11-F17) and (Z)-8-heptadecenyl formate (8-F17), are rarely encountered natural products that are abundant in Sancassania sp. Sasagawa (Acari: Acaridae) mite secretions. Linoleic acid and oleic acid are predicted as key intermediates in the synthesis of the closely related aliphatic formates. To gain insight in this biosynthetic pathway, acarid mite feeding experiments were conducted using ¹³C-labeled precursors to precisely track incorporation. Analyses using ¹³C NMR spectroscopy demonstrated that the ¹³C-labeling pattern of t

SUBMITTER: Shimizu N 

PROVIDER: S-EPMC5347546 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature