Real role of β-blockers in regression of left ventricular mass in hypertension patients: Bayesian network meta-analysis.

ABSTRACT:

Background

Left ventricular hypertrophy (LVH) is commonly present in patients with hypertension (HT). According to the expert consensus document from American, angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blockers (ARBs) were recommended as 1st-line therapeutic drugs. However, none noticed the different efficacy between fat-soluble and selective β1-receptor blockers (FS-β-B) and other β-blockers on regression of LVH before. The aim of this analysis was to compare the efficacy of FS-β-B with the other 4 different classes of antihypertensive drugs (ACEI, ARBs, calcium channel blockers [CCBs], and diuretics) on regression of LVH.

Methods

Relative trials were identified in the PubMed, Web of Science, OVID EBM Reviews and Cochrane databases, and the rel

SUBMITTER: Xing F 

PROVIDER: S-EPMC5348202 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature