The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design.

ABSTRACT: The task of epitope discovery and vaccine design is increasingly reliant on bioinformatics analytic tools and access to depositories of curated data relevant to immune reactions and specific pathogens. The Immune Epitope Database and Analysis Resource (IEDB) was indeed created to assist biomedical researchers in the development of new vaccines, diagnostics, and therapeutics. The Analysis Resource is freely available to all researchers and provides access to a variety of epitope analysis and prediction tools. The tools include validated and benchmarked methods to predict MHC class I and class II binding. The predictions from these tools can be combined with tools predicting antigen processing, TCR recognition, and B cell epitope prediction. In addition, the resource contains a variety of se

SUBMITTER: Fleri W 

PROVIDER: S-EPMC5348633 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature