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Monitoring Cerebral Oxygenation in Neonates: An Update.


ABSTRACT: Cerebral oxygenation is not always reflected by systemic arterial oxygenation. Therefore, regional cerebral oxygen saturation (rScO2) monitoring with near-infrared spectroscopy (NIRS) is of added value in neonatal intensive care. rScO2 represents oxygen supply to the brain, while cerebral fractional tissue oxygen extraction, which is the ratio between rScO2 and systemic arterial oxygen saturation, reflects cerebral oxygen utilization. The balance between oxygen supply and utilization provides insight in neonatal cerebral (patho-)physiology. This review highlights the potential and limitations of cerebral oxygenation monitoring with NIRS in the neonatal intensive care unit.

SUBMITTER: Dix LM 

PROVIDER: S-EPMC5348638 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Monitoring Cerebral Oxygenation in Neonates: An Update.

Dix Laura Marie Louise LM   van Bel Frank F   Lemmers Petra Maria Anna PM  

Frontiers in pediatrics 20170314


Cerebral oxygenation is not always reflected by systemic arterial oxygenation. Therefore, regional cerebral oxygen saturation (rScO<sub>2</sub>) monitoring with near-infrared spectroscopy (NIRS) is of added value in neonatal intensive care. rScO<sub>2</sub> represents oxygen supply to the brain, while cerebral fractional tissue oxygen extraction, which is the ratio between rScO<sub>2</sub> and systemic arterial oxygen saturation, reflects cerebral oxygen utilization. The balance between oxygen s  ...[more]

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