Benefits of resistance exercise in lean women with fibromyalgia: involvement of IGF-1 and leptin.

ABSTRACT:

Background

Chronic pain and fatigue improves by exercise in fibromyalgia (FM) but underlying mechanisms are not known. Obesity is increased among FM patients and associates with higher levels of pain. Symptom improvement after aerobic exercise is affected by body mass index (BMI) in FM. Metabolic factors such as insulin-like growth factor 1 (IGF-1) and leptin may be involved. In this study, the aim was to evaluate the role of metabolic factors in lean, overweight and obese women during resistance exercise, in relation to symptom severity and muscle strength in women with FM.

Methods

Forty-three women participated in supervised progressive resistance exercise, twice weekly for 15-weeks. Serum free and total IGF-1, IGF-binding protein 3 (IGFBP3), adiponectin, leptin and resist

SUBMITTER: Bjersing JL 

PROVIDER: S-EPMC5348801 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature