Multicomponent meningococcal B vaccination (4CMenB) of adolescents and college students in the United States.

ABSTRACT: Meningococcal disease is rare, easily misdiagnosed, and potentially deadly. Diagnosis in the early stages is difficult and the disease often progresses extremely rapidly. In North America, the incidence of invasive meningococcal disease (IMD) is highest in infants and young children, with a secondary peak in adolescents, a population predominantly responsible for the carriage of disease. Neisseria meningitidis serogroup B (MenB) accounts for a large proportion of meningococcal disease in North America, with documented outbreaks in three universities in the United States (US) during 2008-2013. Vaccination is the most effective way to protect against this aggressive disease that has a narrow timeframe for diagnosis and treatment. 4CMenB is a multi-component vaccine against MenB which

SUBMITTER: Banzhoff A 

PROVIDER: S-EPMC5349334 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature