Inhibitory interneuron circuits at cortical and spinal levels are associated with individual differences in corticomuscular coherence during isometric voluntary contraction.

ABSTRACT: Corticomuscular coherence (CMC) is an oscillatory synchronization of 15-35 Hz (β-band) between electroencephalogram (EEG) of the sensorimotor cortex and electromyogram of contracting muscles. Although we reported that the magnitude of CMC varies among individuals, the physiological mechanisms underlying this variation are still unclear. Here, we aimed to investigate the associations between CMC and intracortical inhibition (ICI) in the primary motor cortex (M1)/recurrent inhibition (RI) in the spinal cord, which probably affect oscillatory neural activities. Firstly, we quantified ICI from changes in motor-evoked potentials induced by paired-pulse transcranial magnetic stimulation in M1 during tonic isometric voluntary contraction of the first dorsal interosseous. ICI showed a significant,

SUBMITTER: Matsuya R 

PROVIDER: S-EPMC5349562 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature