Meta-analysis of bariatric surgery versus non-surgical treatment for type 2 diabetes mellitus.

ABSTRACT:

Background

To compare short-term and long-term results of bariatric surgery vs non-surgical treatment for type 2 diabetes mellitus (T2DM).

Methods

A systematic search was conducted in the PubMed, Embase, and Cochrane Library databases for randomized controlled trials (RCTs). All statistical analysis was performed using Review Manager version 5.3. The dichotomous data was calculated using risk ratio (RR) and continuous data was using mean differences (MD) along with 95% confidence intervals (CI).

Results

A total of 8 RCTs with 619 T2DM patients were analyzed. Compared with non-surgical treatment group, bariatric surgery group was associated with higher rate T2DM remission (RR = 5.76, 95%CI:3.15-10.55, P < 0.00001), more reduction HbA1C (MD = 1.29, 95%CI: -1.70 to -0.87

SUBMITTER: Wu GZ 

PROVIDER: S-EPMC5350006 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature