Polymorphisms of Il-10 (-1082) and RANKL (-438) Genes and the Failure of Dental Implants.

ABSTRACT: Background. Genetic polymorphisms in certain cytokines and chemokines have been investigated to understand why some individuals display implant flaws despite having few risk factors at the time of implant. Purpose. To investigate the association of genetic polymorphisms in interleukin- (IL-) 10 [-1082 region (A/G)] and RANKL [-438 region (A/G)] with the failure of dental implants. Materials and Methods. This study included 90 partially edentulous male and female patients who were rehabilitated with a total of 245 Straumann dental implants. An implant was considered a failure if any of the following occurred: mobility, persistent subjective complaint, recurrent peri-implant infection with suppuration, continuous radiolucency around the implant, probing dep

SUBMITTER: Ribeiro R 

PROVIDER: S-EPMC5350407 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature