Ruminant-specific multiple duplication events of PRDM9 before speciation.

ABSTRACT:

Background

Understanding the genetic and evolutionary mechanisms of speciation genes in sexually reproducing organisms would provide important insights into mammalian reproduction and fitness. PRDM9, a widely known speciation gene, has recently gained attention for its important role in meiotic recombination and hybrid incompatibility. Despite the fact that PRDM9 is a key regulator of recombination and plays a dominant role in hybrid incompatibility, little is known about the underlying genetic and evolutionary mechanisms that generated multiple copies of PRDM9 in many metazoan lineages.

Results

The present study reports (1) evidence of ruminant-specific multiple gene duplication events, which likely have had occurred after the ancestral ruminant population diverged from its

SUBMITTER: Padhi A 

PROVIDER: S-EPMC5351255 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature