Improved clinical outcomes of patients with ovarian carcinoma arising in endometriosis.

ABSTRACT:

Background

Despite enormous efforts to dissect the role of endometriosis in ovarian cancer development, the difference in prognosis between ovarian cancer patients with or without endometriosis remains elusive. The purpose of this study is to assess the association between endometriosis and the prognosis in patients with ovarian cancer.

Results

Ovarian cancer arising in endometriosis tended to be presented as clear cell histology, early stage, less intraperitoneal metastasis and ascites, and lower CA125 level compared with those without endometriosis. Multivariate Cox regression analysis identified endometriosis as an independent prognostic factor for progression free survival (P = 0.002) and overall survival (P = 0.009) in all patients and especially for early stage. A nomo

SUBMITTER: Lu J 

PROVIDER: S-EPMC5351594 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature