Joint Estimation of Multiple High-dimensional Precision Matrices.

ABSTRACT: Motivated by analysis of gene expression data measured in different tissues or disease states, we consider joint estimation of multiple precision matrices to effectively utilize the partially shared graphical structures of the corresponding graphs. The procedure is based on a weighted constrained ℓ_∞/ℓ₁ minimization, which can be effectively implemented by a second-order cone programming. Compared to separate estimation methods, the proposed joint estimation method leads to estimators converging to the true precision matrices faster. Under certain regularity conditions, the proposed procedure leads to an exact graph structure recovery with a probability tending to 1. Simulation studies show that the proposed joint estimation methods outperform other methods in g

SUBMITTER: Cai TT 

PROVIDER: S-EPMC5351783 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature