Mechanism study on a plague outbreak driven by the construction of a large reservoir in southwest china (surveillance from 2000-2015).

ABSTRACT:

Background

Plague, a Yersinia pestis infection, is a fatal disease with tremendous transmission capacity. However, the mechanism of how the pathogen stays in a reservoir, circulates and then re-emerges is an enigma.

Methodology/principal findings

We studied a plague outbreak caused by the construction of a large reservoir in southwest China followed 16-years' surveillance.

Conclusions/significance

The results show the prevalence of plague within the natural plague focus is closely related to the stability of local ecology. Before and during the decade of construction the reservoir on the Nanpan River, no confirmed plague has ever emerged. With the impoundment of reservoir and destruction of drowned farmland and vegetation, the infected rodent population previously dis

SUBMITTER: Wang X 

PROVIDER: S-EPMC5352140 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature