Papanicolaou Society of Cytopathology new guidelines have a greater ability of risk stratification for pancreatic endoscopic ultrasound-guided fine-needle aspiration specimens.

ABSTRACT: The Papanicolaou Society of Cytopathology has recently proposed a standardized terminology and nomenclature guidelines for pancreatic cytology. However the risk of malignancy associated with the new guidelines has been scarcely studied. In this study, a series of pancreatic cytology cases obtained by endoscopic ultrasound-guided fine-needle aspiration from 294 Chinese patients were retrospectively re-categorized into six categories according the new guidelines. The risks of malignancy were 18.1% for "negative," 20.0% for "neoplastic," 57.1% for "nondiagnostic," 69.2% for "atypical," 87.5% for "suspicious," and 100.0% for "positive" respectively. The area under the receiver operating characteristic curve was 0.93 (95% Confidence Interval, 0.90-0.96), which was significantly higher than that

SUBMITTER: Chen B 

PROVIDER: S-EPMC5352390 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature